Pharmacology

Lovelace Biomedical’s scientists are experts in more than 100 animal models of disease, encompassing both large and small animals. Board-certified toxicologists (DABT) and pathologists (DACVP), as well as expert biologists, engineers, chemists, statisticians and technical staff are available to support preclinical studies evaluating safety and efficacy. Our scientists bring extensive experience in a wide range of small- and large-molecule delivery methods, including specialty routes, and studies can be supported by our additional expertise in pharmacokinetics, analytical chemistry, toxicology and pathology.

Capabilities

  • Aging and Dementia
  • Allergy
  • Acute lung injury
  • Asthma
  • Chronic heart failure
  • Circulatory shock
  • COPD
  • Colitis
  • Dermatitis
  • Infectious disease (influenza, RSV, bacterial, etc.)
  • Neurology and psychiatry
  • Metabolic disease
  • Pancreatitis
  • Pulmonary fibrosis
  • Pulmonary arterial hypertension
  • Radiation injury
  • Renal Toxin injury
  • Rheumatoid arthritis
  • Spinal cord injury
  • Systemic infection
  • Systemic inflammation
  • Thigh abscess
  • Toxic lung injury
  • Traumatic brain injury
  • Vascular disease
  • Wound healing

Species

  • Non-human primate
  • Gottingen, Yucatan or Yorkshire swine
  • Canine
  • Ferret
  • Guinea pig
  • Rabbit
  • Rat
  • Mouse

Dosing Routes

  • Standard routes: IV, IM, IP, SC, PO
  • Inhalation (nose-only, head-only or whole body)
  • Oral or nasogastric
  • Arterial (hepatic artery, carotid artery or femoral artery)
  • Intravenous infusion: Bolus, intermittent, continuous
  • Ocular
  • Intracerebral or intraventricular